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24566 кн.
This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as...
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In the past 25 years, the distribution of income and wealth in Britain and the US has grown enormously unequal, far more so than in other advanced countries. The book, which is aimed at both an academic and a general audience, examines how this happened, starting with the economic shocks of the 1970s and the neo-liberal policies first applied under Thatcher and Reagan. In essence, growing inequality and economic instability is seen as driven by a US-style model of free-market capitalism that is...
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East Asia has re-emerged after a long eclipse as a centre of world wealth creation and growth. Over the past four decades the region’s share of world GDP has risen from less than 10 to 30 percent, a ratio that is set to rise to 40 percent by 2030. What has made East Asia’s remarkable ascent possible, and what does this economic rebalancing between East and West mean for world politics? In this insightful and provocative book, Philip Golub addresses these questions, tracing the region’s rise from...
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The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each...
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Jerry Fodor is one of the most important philosophers of mind in recent decades. He has done much to set the agenda in this field and has had a significant influence on the development of cognitive science. Fodor's project is that of constructing a physicalist vindication of folk psychology and so paving the way for the development of a scientifically respectable intentional psychology. The centrepiece of his engagement in this project is a theory of the cognitive mind, namely, the computational...
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We are pleased to annouce that God’s Companions by Samuel Wells has been shortlisted for the 2007 Michael Ramsey Prize for theological writing. www.michaelramseyprize.org.uk Grounded in Samuel Wells’ experience of ordinary lives in poorer neighborhoods, this book presents a striking and imaginative approach to Christian ethics. It argues that Christian ethics is founded on God, on the practices of human community, and on worship, and that ethics is fundamentally a reflection of God's abundance....
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This book will describe in detail what it is like to be a parent in four different communities in England. The research data that are the basis for this description are interpreted in relation to a number of key factors, include: family social class, ethnic group, length of time on the neighbourhood and the presence of extended family locally. The book will be of interest to anyone wanting to know more about how to improve the lives of parents and children. Special focus is placed on those...
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Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to 1941, providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological...
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This comprehensive series of volumes on inorganic chemistry provides inorganic chemists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Every volume reports recent progress with a significant, up-to-date selection of papers by internationally recognized researchers, complemented by detailed discussions and complete documentation. Each volume features a complete subject index and the series includes a cumulative index as well.
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Drawing from a lifetime of teaching botany, Dr. Nels Lersten presents the study of the structures and processes involved in the reproduction of plants in his text Flowering Plant Embryology. This richly illustrated reference text, with more than 350 figures and illustrations, presents general angiosperm embryology as it applies to economically important plants. The unique focus on economically important species increases the relevance of this book to today’s students and researchers in the plant...
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In recent years silicon-centered radicals have played an important role in organic synthesis, polymer chemistry and material sciences. The aim of this book is to offer for the first time a description of silyl radicals within an interdisciplinary context, connecting structural characteristics and chemical properties to their application in different areas of chemistry. The first time different aspects of silyl radicals have been brought together Excellent reference tool for experienced...
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The future of Europe and the role it will play in the 21st century are among the most important political questions of our time. The optimism of a decade ago has now faded but the stakes are higher than ever. The way these questions are answered will have enormous implications not only for all Europeans but also for the citizens of Europe’s closest and oldest ally – the USA. In this new book, one of Europe’s leading intellectuals examines the political alternatives facing Europe today and...
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Aristotle is the most influential philosopher of practice, and Knight's new book explores the continuing importance of Aristotelian philosophy. First, it examines the theoretical bases of what Aristotle said about ethical, political and productive activity. It then traces ideas of practice through such figures as St Paul, Luther, Hegel, Heidegger and recent Aristotelian philosophers, and evaluates Alasdair MacIntyre's contribution. Knight argues that, whereas Aristotle's own thought legitimated...
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Kreuzungen zwischen verschiedenen Arten gibt es nicht nur im Tierreich (wie Maultier, Maulesel), sondern auch in hohem Ma?e bei den Holzgewachsen. Lange wurden die Hybriden aus den gangigen Geholzfuhrern ausgeklammert, obwohl sie so essentiell fur die Forstwirtschaft und den Gartenbau sind. Auf diesem Gebiet ist dieses Buch das einzige Werk, das die Erkennungsmerkmale aller 130 Hybridenarten sowie ihrer Eltern tabellarisch auflistet und vergleichend gegenuber stellt. Daher ist eine exakte...
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Dermot Moran provides a lucid, engaging, and critical introduction to Edmund Husserl's philosophy, with specific emphasis on his development of phenomenology. This book is a comprehensive guide to Husserl's thought from its origins in nineteenth-century concerns with the nature of scientific knowledge and with psychologism, through his breakthrough discovery of phenomenology and his elucidation of the phenomenological method, to the late analyses of culture and the life-world. Husserl's complex...
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The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness. This handbook features contributions from such bestselling authors as John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder, and Klaus K. Unger, as well as from scientists working for major companies, including Agilent, AstraZeneca, Merck, Schering, Tosoh...
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This comprehensive, introductory textbook is unique in exploring the emergence of the Hebrew Bible in the broader context of world history. It particularly focuses on the influence of pre-Roman empires, empowering students with a richer understanding of Old Testament historiography. Provides a historical context for students learning about the development and changing interpretations of biblical texts Examines how these early stories were variously shaped by interaction with the Mesopotamian and...
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There are hardly more versatile compounds in organic synthesis than carbene complexes. The rapid development of new synthetic methods involving carbene complexes – stereoselective cyclopropanation, carbonyl olefination, olefin metathesis, etc. – reveals the value and high potential of these compounds. Their application ranges from the synthesis of fine chemicals to polymer production. This comprehensive, well structured handbook presents the fundamental principles and the recent advances in...
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The Blackwell Companion to Christian Spirituality is a comprehensive single-volume introduction to Christian spirituality, and represents the most significant recent developments in the field. Offers a thoroughly interdisciplinary, broadly ecumenical, and representative overview of the most significant recent developments in the field Comprises essays combining rigorous academic scholarship with accessible and elegant writing Reflects an understanding of the field as the study of the lived...
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This book provides a clear and comprehensive introduction to the work of Willard van Orman Quine, the most important and influential American philosopher of the post-war period. An understanding of Quine's work is essential for anyone who wishes to follow contemporary debates in the philosophy of language, the philosophy of mind and metaphysics. Hookway traces the development of Quine's work from his early criticisms of logical positivism and empiricism to his more recent theories about mind and...
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The paradigm of ‘multi-agent’ cooperative control is the challenge frontier for new control system application domains, and as a research area it has experienced a considerable increase in activity in recent years. This volume, the result of a UCLA collaborative project with Caltech, Cornell and MIT, presents cutting edge results in terms of the “dimensions” of cooperative control from leading researchers worldwide. This dimensional decomposition allows the reader to assess the multi-faceted...
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Written by contributors from around the world, The International Handbook of Stepfamilies: Policy and Practice in Legal, Research, and Clinical Environments is a collection of research, legal, and clinical recommendations that fills a growing need for complex, re-formed families. Using the information in this book, which includes contemporary research and its implications, you will be able to consider stepfamilies in an international context. Understand the issues that clinicians face when they...
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In this major new work, Bernstein explores the ethical and political dimensions of the modernity/post-modernity debate. Bernstein argues that modernity / post-modernity should be understood as a kind of mood – one which is amorphous, shifting and protean but which exerts a powerful influence on our current thinking. Focusing on thinkers such as Heidegger, Derrida, Foucault, Habermas and Rorty, Bernstein probes the strengths and weaknesses of their work, and shows how they have contributed to the...
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As phenols represent an important functional group category, The Chemistry of Phenols is an essential addition to any chemistry library. Written by experts, all aspects concerning these compounds are covered making this an essential reference book, bringing together invaluable information into one source for organic, organometallic chemists as well as chemists from a variety of other organic sub-disciplines. Single Source information – essential for organic, organometallic and chemists from...
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