Химия
1580 кн.
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in...
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Eine bunte und uberraschende Abenteuerreise durch die faszinierenden Weiten des Chemie-Universums: Wie erklart die Chemie die Entstehung des Lebens, wie hat sie die Welt verandert und wie lassen sich die drangenden Probleme unserer Zeit mit ihrer Hilfe losen? In zwolf Kapiteln geben uns ausgesuchte Spezialisten, Chemiker und Chemikerinnen einen Einblick in die Chemie als au?erst kreative und verantwortungsbewusste Wissenschaft. Viele praktische Beispiele, Produkte und Anwendungen zeigen das...
| Автор | Hans-Jürgen Quadbeck-Seeger |
Details the source, release, exposure, adsorption, aggregation, bioavailability, transport, transformation, and modeling of engineered nanoparticles found in many common products and applications Covers synthesis, environmental application, detection, and characterization of engineered nanoparticles Details the toxicity and risk assessment of engineered nanoparticles Includes topics on the transport, transformation, and modeling of engineered nanoparticles Presents the latest developments and...
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Provides a comprehensive review of all types of medical therapeutic delivery solutions from traditional pharmaceutical therapy development to innovative medical device therapy treatment to the recent advances in cellular and stem cell therapy development • Provides information to potentially allow future development of treatments with greater therapeutic potential and creativity • Includes associated regulatory requirements for the development of these therapies • Provides a comprehensive...
| Автор | Chung Chow Chan |
Edited by a team of highly respected researchers combining their expertise in chemistry, physics, and medicine, this book focuses on the use of ruthenium-containing complexes in artificial photosynthesis and medicine. Following a brief introduction to the basic coordination chemistry of ruthenium-containing complexes and their synthesis, as well as their photophysical and photochemical properties, the authors discuss in detail the major concepts of artificial photosynthesis and mechanisms of...
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A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors. Relevant to all those within the scientific community dealing with Raman Spectroscopy, i.e. physicists, chemists, biologists, material scientists, physicians and biomedical scientists. SERS applications are widely...
| Автор | Katrin Kneipp |
Catalysts speed up a chemical reaction or allow for reactions to take place that would not otherwise occur. The chemical nature of a catalyst and its structure are crucial for interactions with reaction intermediates. An electrocatalyst is used in an electrochemical reaction, for example in a fuel cell to produce electricity. In this case, reaction rates are also dependent on the electrode potential and the structure of the electrical double-layer. This work provides a valuable overview of this...
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This volume will be summarized on the basis of the topics of Ionic Liquids in the form of chapters and sections. It would be emphasized on the synthesis of ILs of different types, and stabilization of amphiphilic self-assemblies in conventional and newly developed ILs to reveal formulation, physicochemical properties, microstructures, internal dynamics, thermodynamics as well as new possible applications. It covers: Topics of ionic liquid assisted micelles and microemulsions in relation to their...
| Автор | Bidyut K. Paul |
A valuable handbook containing reviews, practical methods and standard operating procedures. A valuable and practical working handbook containing introductory and specialist content that tackles a major and growing field of environmental, microbiological and ecotoxicological monitoring and analysis Includes introductory reviews, practical analytical chapters and a comprehensive listing of almost thirty Standard Operating Procedures (SOPs) For use in the laboratory, in academic and government...
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Written by a well-respected and experienced author, this textbook fills the gap for a concise introduction to the key concepts of organic stereochemistry and the most important classical and modern methods in stereoselective synthesis. The concepts are extensively illustrated in color, with practical examples and question-answer sets to help consolidate the reader's knowledge. In addition, animations are available from the Wiley website. A must-have for students in chemistry, biochemistry, and...
| Автор | Gábor Hornyánszky |
Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list...
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In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this...
| Автор | Frederick Harris |
In the nematic liquid crystal phase, rod-shaped molecules move randomly but remain essentially parallel to one another. Biaxial nematics, which were first predicted in 1970 by Marvin Freiser, have their molecules differentially oriented along two axes. They have the potential to create displays with fast switching times and may have applications in thin-film displays and other liquid crystal technologies. This book is the first to be concerned solely with biaxial nematic liquid crystals, both...
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The current state of the science supporting new research in lysophospholipids The study of lysophospholipids exploded with the discovery of cell surface receptors on both lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Since then, thousands of original research reports—ranging from fundamental cell signaling to the physiology and pathophysiology of individual organ systems—have centered on lysophospholipids. This book draws together and analyzes the current literature to provide...
| Автор | Jerold Chun |
Demonstrates how advances in plant chemical biology can translate to field applications With contributions from a team of leading researchers and pioneers in the field, this book explains how chemical biology is used as a tool to enhance our understanding of plant biology. Readers are introduced to a variety of chemical biology studies that have provided novel insights into plant physiology and plant cellular processes. Moreover, they will discover that chemical biology not only leads to a...
| Автор | Dominique Audenaert |
A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial...
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Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and...
| Автор | Wilfried M. A. Niessen |
This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the...
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Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of «personalized drugs» are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of...
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The comprehensive resource for understanding the structure, properties, and applications of cyclodextrins Cyclodextrins: Properties and Industrial Applications is a comprehensive resource that includes information on cyclodextrins (CDs) structure, their properties, formation of inclusion complex with various compounds as well as their applications. The authors Sahar Amiri and Sanam Amiri, noted experts in the field of cyclodextrins, cover both the basic and applied science in chemistry, biology,...
| Автор | Sahar Amiri |
This book reflects the increasing interest among the chemical synthetic community in the area of asymmetric copper-catalyzed reactions, and introduces readers to the latest, most significant developments in the field. The contents are organized according to reaction type and cover mechanistic and spectroscopic aspects as well as applications in the synthesis of natural products. A whole chapter is devoted to understanding how primary organometallics interact with copper to provide selective...
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Alle relevanten Aspekte der Analytischen Chemie werden in diesem Lehrbuch, das gleichzeitig auch als Referenz fur Praktiker dient, umfassend und klar auf den Punkt gebracht. Das Autorenteam wird durch zwei aktive und international bekannte Professoren verstarkt; dies sorgt fur frischen Wind, gleichzeitig wird der didaktisch ausgefeilte Stil der Vorauflagen beibehalten. Von der Analysenstrategie zur Probenvorbereitung, von der Ma?analyse uber spektroskopische und chromatographische Methoden bis...
| Автор | Prof. Georg Schwedt |
Written by established experts in the field, this book features in-depth discussions of proven scientific principles, current trends, and applications of nuclear chemistry to the sciences and engineering. • Provides up-to-date coverage of the latest research and examines the theoretical and practical aspects of nuclear and radiochemistry • Presents the basic physical principles of nuclear and radiochemistry in a succinct fashion, requiring no basic knowledge of quantum mechanics • Adds...
| Автор | Walter D. Loveland |
Using a collaborative and interdisciplinary author base with experience in the pharmaceutical industry and academia, this book is a practical resource for high content (HC) techniques. • Instructs readers on the fundamentals of high content screening (HCS) techniques • Focuses on practical and widely-used techniques like image processing and multiparametric assays • Breaks down HCS into individual modules for training and connects them at the end • Includes a tutorial chapter that works through...
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