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Carbohydrate-based Drug Discovery

Chi-Huey Wong

Carbohydrate-based Drug Discovery

To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates >...

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Chi-Huey Wong

Surfactants from Renewable Resource...

Ingegard Johansson

Surfactants from Renewable Resources

Most modern surfactants are readily biodegradable and exhibit low toxicity in the aquatic environment, the two criteria for green surfactants. However the majority are synthesised from petroleum, so over the past decade the detergent industry has turned its attention to developing greener routes to create these surfactants via renewable building blocks. Surfactants from Renewable Resources presents the latest research and commercial applications in the emerging field of sustainable surfactant...

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Ingegard Johansson

Fundamentals of Early Clinical Drug...

Stéphane Caron

Fundamentals of Early Clinical Drug Development

An informative look at the intricacies of today's drug development process Once a discovery organization has identified a potential new drug candidate, it is the daunting task of synthetic organic chemists to identify the chemical process suitable for preparation of this compound in a highly regulated environment. Only through a multi-layered chemical process that takes into account such factors as safety, environmental considerations, freedom to operate and cost-effectiveness can researchers...

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Stéphane Caron

Indoor Environment

Tunga Salthammer

Indoor Environment

Covering the fundamentals of air-borne particles and settled dust in the indoor environment, this handy reference investigates: * relevant definitions and terminology, * characteristics, * sources, * sampling techniques and instrumentation, * exposure assessment, * monitoring methods. The result is a useful and comprehensive overview for chemists, physicists and biologists, postgraduate students, medical practitioners, occupational health professionals, building owners and managers, building,...

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Tunga Salthammer

Superacid Chemistry

Jean Sommer

Superacid Chemistry

The chemistry of superacids has developed in the last two decades into a field of growing interest and importance. Now available in a new expanded second edition, this definitive work on superacids offers a comprehensive review of superacids and discusses the development of new superacid systems and applications of superacids in the promotion of unusual reactions. Covering Bronsted and Leurs superacids, solid superacids, carbocations, heterocations, and catalyzed reactions, this timely volume is...

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Jean Sommer

Additives for Coatings

Johan Bieleman

Additives for Coatings

No doubt: A perfect coating has to look brilliant! But other properties of coatings are also most important. Coatings have to be durable, tough and easily applicable. Additives are the key to success in achieving these characteristics, even though the amounts used in coating formulations are small. It is not trivial at all to select the best additives. In practice, many series of tests are often necessary, and the results do not explain, why a certain additive improves the quality of a coating...

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Johan Bieleman

Organic Synthesis

Douglass Taber F.

Organic Synthesis

The second volume in a series, Organic Synthesis: State of the Art 2005-2007 will provide you with a convenient, compact summary of the state of the art of organic synthesis. This reference guide will quickly lead you to the most important recent developments like how scientists can now prepare ketones by directly combining aldehydes with terminal alkenes. Inside, you will find detailed analysis of more than twenty total syntheses, including the Davies Synthesis of (-)-Colombiasin A and...

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Douglass Taber F.

Antigen Presenting Cells

Harald Kropshofer

Antigen Presenting Cells

This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. Structured in a clear way to allow access to a very broad readership, the book is written from the viewpoint of a biochemist, immunologist, and scientist with...

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Harald Kropshofer

Novel Vaccination Strategies

Stefan H. E. Kaufmann

Novel Vaccination Strategies

The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New...

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Stefan H. E. Kaufmann

Integration of Omics Approaches and...

Antonia Vlahou

Integration of Omics Approaches and Systems Biology for Clinical Applications

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs,...

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Antonia Vlahou

Vascular Development

Jamie Goode A.

Vascular Development

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a...

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Jamie Goode A.

Organofluorine Chemistry

Kenji Uneyama

Organofluorine Chemistry

The replacement of hydrogen with fluorine in organic molecules can profoundly influence their chemical and physical properties, leading to a range of compounds with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, so that organofluorine chemistry is economically highly important. Organofluorine Chemistry will help chemists to develop a systematic knowledge of the chemistry of fluorine with a view towards its...

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Kenji Uneyama

Modern Heterogeneous Oxidation Cata...

Noritaka Mizuno

Modern Heterogeneous Oxidation Catalysis

Filling a gap in the current literature, this comprehensive reference presents all important catalyst classes, including metal oxides, polyoxometalates, and zeolites. Readers will find here everything they need to know – from structure design to characterization, and from immobilization to industrial processes. A true must-have for anyone working in this key technology.

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Noritaka Mizuno

Adhesives and Adhesive Tapes

Gerhard Gierenz

Adhesives and Adhesive Tapes

Adhesion is among the oldest technologies known to mankind, but the technology of adhesives began to boom with the developments in chemistry in the early 1900s. The last few years have seen tremendous progress in the performance of adhesives, allowing two pieces to be connected inseparably. Modern adhesives perform so well that more sophisticated joining methods, e.g. welding, can often be replaced by adhesion, meaning that adhesives have found new areas of application. This book allows readers...

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Gerhard Gierenz

Germline Development

Joan Marsh

Germline Development

Connects classical cellular descriptive studies with more recent work on the molecular and genetic aspects regarding germline development. Prominent scientists discuss research on a range of organisms including insects, worms, birds, fish, amphibia, mammals and green algae. Specification of germ cells, their migration to the gonads and subsequent interactions with the soma and evolutionary factors of their segregation are among the topics covered.

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Joan Marsh

Practical Biotransformations

Gideon Grogan

Practical Biotransformations

The development of new asymmetric catalytic methods is of fundamental importance to industrial synthetic chemistry. The demand for optically pure synthetic intermediates and the drive to adopt greener methods of synthesis have stimulated a growing interest in biocatalysis as a selective and environmentally benign synthetic technique. Practical Biotransformations: A Beginner's Guide provides an introduction to microbes and enzymes and demonstrates their practical applications in synthetic organic...

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Gideon Grogan

Phenotypic and Genotypic Diagnosis...

Muin S. A. Tuffaha

Phenotypic and Genotypic Diagnosis of Malignancies

Carefully designed as an easy and quick reference, this desktop manual is for working pathologists who need to determine the particular type of cancer they are dealing with in a patient. To this end, the book contains many large tables of information to allow a fast analysis of results, providing all the relevant information to diagnose the full range of different tumors in humans. Must-have content for all cancer pathologists.

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Muin S. A. Tuffaha

Sedimentary Facies Analysis

A. Plint Guy

Sedimentary Facies Analysis

This book celebrates the professional career of Harold Reading, who has played a leading role in the development of the IAS, and has been at the roots of the development of 'facies sedimentology' as an art in itself and as a major tool in the broader field of geology. This special collection of original research papers from Harold Reading's students covers the wide range of his research interests and reflects the power of facies sedimentology today. State-of-the-art research papers in the...

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A. Plint Guy

Advances in Chemical Physics, Volum...

Ilya Prigogine

Advances in Chemical Physics, Volume 31

The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.

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Ilya Prigogine

Correlation Spectroscopy of Surface...

Jamal Berakdar

Correlation Spectroscopy of Surfaces, Thin Films, and Nanostructures

Here, leading scientists present an overview of the most modern experimental and theoretical methods for studying electronic correlations on surfaces, in thin films and in nanostructures. In particular, they describe in detail coincidence techniques for studying many-particle correlations while critically examining the informational content of such processes from a theoretical point viewpoint. Furthermore, the book considers the current state of incorporating many-body effects into theoretical...

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Jamal Berakdar

Optical Imaging and Spectroscopy

David Brady J.

Optical Imaging and Spectroscopy

An essential reference for optical sensor system design This is the first text to present an integrated view of the optical and mathematical analysis tools necessary to understand computational optical system design. It presents the foundations of computational optical sensor design with a focus entirely on digital imaging and spectroscopy. It systematically covers: Coded aperture and tomographic imaging Sampling and transformations in optical systems, including wavelets and generalized sampling...

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David Brady J.

Advances in Chemical Physics. Volum...

Stuart A. Rice

Advances in Chemical Physics. Volume 131

This series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 131 includes chapters on: Polyelectrolyte Dynamics; Hydrodynamics and Slip at the Liquid-Solid Interface; Structure of Ionic Liquids and Ionic Liquid Compounds: Are Ionic Liquids Genuine Liquids in the Conventional Sense?; Chemical Reactions at Very High Pressure; Classical Description of Nonadiabatic Quantum Dynamics; and Non-Born Oppenheimer...

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Stuart A. Rice

An Introduction to Tissue-Biomateri...

Rena Bizios

An Introduction to Tissue-Biomaterial Interactions

An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized...

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Rena Bizios

Phaselock Techniques

Floyd Gardner M.

Phaselock Techniques

A greatly revised and expanded account of phaselock technology The Third Edition of this landmark book presents new developments in the field of phaselock loops, some of which have never been published until now. Established concepts are reviewed critically and recommendations are offered for improved formulations. The work reflects the author's own research and many years of hands-on experience with phaselock loops. Reflecting the myriad of phaselock loops that are now found in electronic...

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Floyd Gardner M.

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