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Intracranial Gliomas Part III - Inn...

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Intracranial Gliomas Part III - Innovative Treatment Modalities

At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon...

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Disorders of Fluid and Electrolyte...

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Disorders of Fluid and Electrolyte Metabolism

It is well known that acute, severe hyponatremia is a life-threatening situation. However, there is growing evidence that mild and chronic hyponatremia may also have negative consequences. Gait disturbances, attention deficits, falls and fractures, and bone loss have all been reported, with increased mortality in almost every disease state if the patient is hyponatremic. This book has been written by key opinion leaders in the field and covers a spectrum of crucial aspects of hyponatremia,...

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Oral Biofilms

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Oral Biofilms

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CKD-Associated Complications: Progr...

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CKD-Associated Complications: Progress in the Last Half Century

This publication is a record of some of the outstanding presentations given at the 63rd Annual Meeting of the Japanese Society for Dialysis Therapy (JSDT). The meeting was held in Kobe in 2018, celebrating the 50-year anniversary of the founding of the JSDT as a voluntary academic association. Therapy for end-stage kidney disease (ESKD) now faces vital issues besides the management of renal anemia and chronic kidney disease-mineral and bone disorder and the selection of the optimal treatment...

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Pearls and Pitfalls in Head and Nec...

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Pearls and Pitfalls in Head and Neck Surgery

In this unique volume, leading international experts share their experiences in the management of head and neck tumors, providing a guidebook for all surgeons dealing with head and neck neoplasms. Each chapter offers a concise description of useful 'pearls' and dangerous 'pitfalls' which must be avoided. Contributions cover topics from thyroid glands, neck metastases, and oral tumors to laryngeal, pharyngeal, and nasopharyngeal tumors, as well as salivary gland tumors, skull...

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Recent Advances in the Pathogenesis...

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Recent Advances in the Pathogenesis and Treatment of Kidney Diseases

Chronic kidney disease (CKD) is a global health burden with associated high economic costs to the health system. Main factors are the increasing number of patients with diabetes and hypertension and the aging of the population. CKD has been associated with increased risks of cardiovascular morbidity, premature mortality, and/or decreased quality of life. In this new volume, renowned Japanese scientists present their recent research results. Papers cover various aspects of kidney diseases such as...

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Knowing One's Medical Fate in Advan...

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Knowing One's Medical Fate in Advance

Modern medicine is now in a position to make advanced prognoses that chart the entire course of illness and recovery. Paradoxically, this is coupled with a new dimension of uncertainty for the patient, i.e. coming to terms with discovering they have an increased risk of a particular disease and deciding what appropriate steps to take. In this publication, renowned experts in their fields discuss these issues. The certainty and uncertainty of one’s fate are discussed from both methodological and...

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New Concepts for Human Disorders of...

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New Concepts for Human Disorders of Sexual Development

In the last few years, impressive research has been done on disorders of sex development (DSD), largely expanding the physiopathology with relevant effects on practice. Thus, management of individuals with DSD requires updated scientific knowledge, integrating basic and clinical information. In addition, doctors involved in the care of individuals with DSD need to develop specific personal skills in communication, ethics, legal issues and the ability to work together in dedicated...

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Practical Algorithms in Pediatric G...

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Practical Algorithms in Pediatric Gastroenterology

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Paul Klee and His Illness

H. Suter

Paul Klee and His Illness

In 1933 Paul Klee’s work was branded as ‘Entartete Kunst’ (Degenerate Art) by the National Socialists and he was dismissed from his professorial post at the Düsseldorf Academy of Fine Arts. This led him, together with his wife Lily, to return to his ‘real home’ of Bern. Here his avant-garde art was not understood and Klee found himself in unasked for isolation. In 1935 Klee started to suffer from a mysterious disease. The symptoms included changes to the skin and problems with the internal...

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H. Suter

Nutrition Education: Strategies for...

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Nutrition Education: Strategies for Improving Nutrition and Healthy Eating in Individuals and Communities

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Remote Patient Management in Perito...

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Remote Patient Management in Peritoneal Dialysis

Telemedicine and remote patient monitoring are innovative tools to provide remote transmission, interpretation, and storage of data for review by the care team. These tools allow for accurate home monitoring of patients enabling the team to improve care through prevention and early identification of problems. This book is structured into four main parts. The first describes the evolution of peritoneal dialysis and related technology. The second part summarizes current unmet clinical needs...

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Guide for Investigator Initiated Tr...

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Guide for Investigator Initiated Trials

For academic medical faculty unfamiliar with national and international regulations, the prospect of initiating and managing a clinical trial can be intimidating. The development of protocols and case report forms, compliance with regulatory requirements, the monitoring of clinical trials as well as the responsibilities of documentation are just some of the tasks the sponsor-investigator is faced with. This book covers the entire spectrum of a clinical trial, reviewing the different stages step...

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Hypopharyngeal Cancer

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Hypopharyngeal Cancer

In most published literature hypopharyngeal cancer is discussed in combination with larynx cancer. This volume is dedicated exclusively to hypopharyngeal cancer. It is a compilation by recognized head and neck oncology experts, who have extracted from published literature and from their own clinical practice, an up-to-date review and commentary on the management of hypopharyngeal cancer. All aspects of hypopharyngeal cancer have been reviewed. They include epidemiology, diagnosis, staging of...

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Diabetic Retinopathy and Cardiovasc...

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Diabetic Retinopathy and Cardiovascular Disease

Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the...

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The Na+, K+ Pumps Keep Us Going

Torben Clausen

The Na+, K+ Pumps Keep Us Going

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Torben Clausen

Current Perspectives in Kidney Dise...

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Current Perspectives in Kidney Diseases

After years of stagnation, much has been happening in the diagnosis and treatment of kidney diseases. This book contains a comprehensive review of the main developments in AKI, CKD, hemodialysis and kidney transplantation. The section on AKI deals with the key innovations in extracorporeal technologies. The section on nephrology and CKD concentrates on mineral metabolism alterations, restenosis in hemodialytic fistulas, mycophenolate mofetil as an alternative treatment for IgA nephropathy, and...

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Guide to Paediatric Drug Developmen...

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Guide to Paediatric Drug Development and Clinical Research

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Imaging Techniques

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Imaging Techniques

The introduction of new imaging methods has revolutionized the management of retinal diseases. Techniques like OCT angiography and fundus autofluorescence imaging have enabled the exploration of new perspectives for understanding the progress of diseases such as age-related macular degeneration (AMD) and diabetic retinopathy. Multimodal imaging of the retina will open new avenues for an integrated diagnostic approach in the future. This publication – like all volumes of the ‘ESASO Course Series’...

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The Craniocervical Syndrome and MRI

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The Craniocervical Syndrome and MRI

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Chronotherapeutics for Affective Di...

M. Terman

Chronotherapeutics for Affective Disorders

Light therapy' is established worldwide as the treatment of choice for seasonal affective disorder. It is also successfuly used in nonseasonal depression, as well as for many other psychiatric and neurologic illnesses, and in sleep medicine. ‘Wake therapy’ is the fastest antidepressant known. Imaging studies show that both methods share neurobiological substrates with antidepressants, but act much faster. 'Chronotherapeutics' – the combination of light and wake therapy –...

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M. Terman

Human Milk: Composition, Clinical B...

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Human Milk: Composition, Clinical Benefits and Future Opportunities

Human milk contains all of the essential nutrients and other functional components thought to have short- and long-term neonatal health benefits, such as positive biological effects on growth, metabolism, cognition, and immunity. This publication brings together the world’s experts who touch on the spectrum of current knowledge, from the history and mechanics of breastfeeding, its physiological and clinical effects, to the new surprises revealed by metabolomics and comparative biology. One of...

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Caries Excavation: Evolution of Tre...

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Caries Excavation: Evolution of Treating Cavitated Carious Lesions

Currently there is no reason, in most cases of cavitated caries lesions, to remove affected tissue. This book presents evidence-based research on the topic and provides assessments of diagnostic devices. It offers new insights into how a dentine carious cavity can be managed by either tissue removal or restoration. Methods for preserving dental tissue are presented and ample evidence highlights the need to seal with a quality restorative material. An update on how to conduct a randomized...

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Leptospirosis and the Kidney

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Leptospirosis and the Kidney

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