Медицина
10796 кн.
The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects. The first and only book to cover neutralization in connection with biopharmaceuticals and the measurement and...
| Автор | Michael Tovey G. |
The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics,...
| Автор | Sheila Peters Annie |
Stillbirth remains a major and tragic obstetric complication The number of deaths due to stillbirth are greater than those due to preterm birth and sudden infant death syndrome combined. Stillbirth: Prediction, Prevention and Management provides a comprehensive guide to the topic of stillbirth. Distilling recent groundbreaking research, expert authors consider: The epidemiology of stillbirth throughout the world The various possible causes of stillbirth The psychological effects on mothers and...
| Автор | Catherine Spong Y. |
American health care has made great strides in the past hundred years. Life expectancy has increased dramatically and advances in medicine and treatments have eradicated many life-threatening diseases. However, in today's health care arena there is divergence between our health needs, the structure of our health care system, and how health care is delivered and funded. In Forces of Change, David A. Shore has collected the leading thinking from experts in the field on how our health care system...
| Автор | David Shore A. |
The importance of appropriate and effective management of patient with long term chronic conditions cannot be underestimated. Case Management of Long-Term Conditions aims to provide all appropriate practitioners (including nurses, pharmacists, physiotherapists, and social care practitioners) who might be involved in delivery of proactive case management with a practical understanding of how their knowledge and skills can be utilised to improve outcomes for people with chronic long-term...
| Автор | Janet Snoddon |
Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature,...
| Автор | George Billman Edward |
An essential introduction to conducting the various stages of medical device clinical trials Clinical research continues to be one of the most vital components of pharmaceutical, biostatistical, and medical studies. Design, Execution, and Management of Medical Device Clinical Trials provides a uniform methodology for conducting and managing clinical trials. Written in a style that is accessible to readers from diverse educational and professional backgrounds, this book provides an in-depth and...
| Автор | Salah Abdel-aleem M. |
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of preclinical development activities and their interplay in effectively identifying successful clinical candidates, the book helps pharmaceutical...
| Автор | Mitchell Cayen N. |
Clinical Small Animal Care: Promoting Patient Health through Preventative Nursing is an introduction to the principles of day-to-day veterinary practice, with coverage ranging from the initial assessment, fluid therapy monitoring, and perioperative management to care of animals with specific diseases. The book offers concrete guidance on best practices for promoting patient health in veterinary care, emphasizing specific techniques to prevent complications before they happen. A practical,...
| Автор | Kimm Wuestenberg |
Ethical medical practice and treatment in psychiatry are based on the concept of first do no harm. However, this cannot, and does not, apply to forensic cases where there is no doctor–patient relationship and the forensic psychiatrist may indeed cause harm to the examinee. In this book, Robert Sadoff analyzes the ethical issues affecting forensic psychiatric practice, especially those promulgated by the American Academy of Psychiatry and the Law. Within those guidelines, he looks at individual...
| Автор | Robert Sadoff L. |
Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit of a certain treatment, the strict patient selection criteria, poor compliance and high drop-out rate leave the conclusions open to question. Are the new treatments really better or more cost-effective than the old? Do they have...
| Автор | Adler Lawrence |
Orthodontic Retainers and Removable Appliances – Principles of Design and Use is a unique practical guide for dental students, general dental practitioners, orthodontic students, therapists and others who have an interest in knowing how to design, fit, adjust and maintain retainers (both fixed and removable) and removable orthodontic appliances. The book offers step-by-step instructions alongside clear illustrations within the key areas of clinical orthodontic practice. In each case, information...
| Автор | Luther Friedy |
The last decade has seen an explosion of medical information in regards to the nutrition care and management of children. While nutritional therapies have expanded, the treatment choices have become increasingly complex. This exciting title addresses the extensive amount of information available to practitioners in a concise, accessible fashion via a series of algorithms. It focuses on the normal growing healthy child from birth through adolescence, covering common pediatric diseases and...
| Автор | Suskind David |
Following the undergraduate curriculum set by the British Association of Urological Surgeons, Urology at a Glance offers practical advice on diagnosis and management of one of the most rapidly developing medical specialties. Building on basic science, the book provides an overview of clinical approaches to assist the medical student or junior doctor on rotation, as well as looking at practical procedures and specific details of the most commonly encountered urological disorders. Vibrantly...
| Автор | Hashim Hashim |
The traditional agents for controlling the levels of glucose in the blood remain important therapies but they have their downside from the point of view of tolerability and side effects. Moreover, they appear not to be able to counter the natural history deterioration of the disease in terms of the onset of diabetic-related complications. Recent years have seen an influx of new treatment therapies and technologies aimed at achieving better glycaemic control for diabetic patients such as...
| Автор | Battelino Tadej |
Simulated Patient Methodology is a timely book, aimed at health professional educators and Simulated Patient (SP) practitioners. It connects theory and evidence with practice to ensure maximum benefit for those involved in SP programmes, in order to inform practice and promote innovation. The book provides a unique, contemporary, global overview of SP practice, for all health sciences educators. Simulated Patient Methodology: • Provides a cross-disciplinary overview of the field • Considers...
| Автор | Bearman Margaret |
There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in...
| Автор | Ramoni Marco |
Offers a fresh perspective on how conversation analysis can be used to highlight the sophisticated nature of what children actually do when interacting with their peers, parents, and other adults. Brings together a contributor team of leading experts in the emerging field of child-focused conversation analytic studies, from both academic and professional research backgrounds Includes examples of typically developing children and those who face a variety of challenges to participation, as they...
| Автор | Forrester Michael |
Human Oral Mucosa: Development, Structure and Function is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial...
| Автор | Brogden Kim |
Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative...
| Автор | Crichton Robert |
Critical Care Nursing: Learning from Practice takes a unique approach to critical care. Based around case scenarios that have the patient as the central focus, each chapter is constructed around an example of a critically ill patient with specific care needs. The chapters then go on to critically explore the knowledge and skills required to deliver expert care. This book looks at a range of critical care scenarios, including: The patient with acute lung injury The patient with fever The patient...
| Автор | Brown Kate |
Research is a fundamental part of midwifery practice. However, not everyone finds it easy to understand the basic principles, and particularly the language of research. This accessible handbook enables midwives and student midwives to firstly understand how to search and make sense of research evidence, how to write a research proposal and finally how to undertake a research study. The Handbook of Midwifery Research specifically focuses on the needs of midwives and students and helps increase...
| Автор | Steen Mary |
This international primer on psycho-oncology spans settings of care as well as regional boundaries. Designed to be easy to read, with informaton clearly displayed in concise tables and boxes accompanied by clinical vignettes, the book provides clear, practical guidance on all aspects of the psychological care of patients with cancer. Both trainees and practitioners will find it useful in the clinic as well as a resource for continued professional development.
| Автор | Grassi Luigi |
Parasitology: An Integrated Approach, provides a concise, student-friendly account of parasites and parasite relationships that is supported by case studies and suggestions for student projects. The book focuses strongly on parasite interactions with other pathogens and in particular parasite-HIV interactions, as well as looking at how host behaviour contributes to the spread of infections. There is a consideration of the positive aspects of parasite infections, how humans have used parasites...
| Автор | Gunn Alan |