Gregory Bock R.

37 кн. Подписаться на автора

Сортировать по:

дате добавления

названию

году выхода

количеству скачиваний

'In Silico' Simulation of Biologica...

Gregory Bock R.

'In Silico' Simulation of Biological Processes

Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current...

Автор

Gregory Bock R.

Anaphylaxis

Gregory Bock R.

Anaphylaxis

Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding prevalence, estimates regarding insect sting anaphylaxis range from 1-3% in the general population, but much higher values have been reported by some authors for food and drug-induced anaphylaxis. Anaphylaxis is the main acute killer of allergic individuals. Although anaphylaxis was discovered at the...

Автор

Gregory Bock R.

Autism

Gregory Bock R.

Autism

This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of the whole spectrum of study of this disorder. It covers four main areas: Twin and family studies indicate that the heritability of the underlying liability to autism exceeds 90% and point to a multifactorial causation, involving a relatively small number...

Автор

Gregory Bock R.

Biology of IGF-1

Gregory Bock R.

Biology of IGF-1

An invaluable book containing a series of interdisciplinary discussions between clinical and basic scientists. Biology of IGF-1: Its interaction with insulin and health and malignant states focuses on key issues such as: the definition of danger zones the development of methods for early recognition of malignant states linked to IGF-1 and/or insulin possible approaches to preventative intervention the relevance in this field of research to the development of novel therapeutic approaches to...

Автор

Gregory Bock R.

Cortical Development

Gregory Bock R.

Cortical Development

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system. Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical...

Автор

Gregory Bock R.

Decoding the Genomic Control of Imm...

Gregory Bock R.

Decoding the Genomic Control of Immune Reactions

This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and...

Автор

Gregory Bock R.

Defining Optimal Immunotherapies fo...

Gregory Bock R.

Defining Optimal Immunotherapies for Type 1 Diabetes

This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials. The book integrates information from human and animal studies. The book considers T1D within the broader context of autoimmune disease. The...

Автор

Gregory Bock R.

Dietary Supplements and Health

Gregory Bock R.

Dietary Supplements and Health

Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons: to enhance «well-being», as traditional medicines, for health promotion or disease risk reduction, and as alternatives or complements to conventional drug therapies. On a global basis, the dietary supplement industry has enjoyed rapid growth, becoming a...

Автор

Gregory Bock R.

Empathy and Fairness

Gregory Bock R.

Empathy and Fairness

Empathy is the process that allows us to share the feelings and emotions of others, in the absence of any direct emotional stimulation to the self. Humans can feel empathy for other people in a wide array of contexts: for basic emotions and sensation such as anger, fear, sadness, joy, pain and lust as well as for more complex emotions such as guilt, embarrassment and love. It has been proposed that, for most people, empathy is the process that prevents us doing harm to others. Although empathy...

Автор

Gregory Bock R.

Environmental Statistics

Gregory Bock R.

Environmental Statistics

Environmental statistics is a rapidly growing discipline that is important not only as a division of professional and academic statistics, but also in the accumulation of data on environmental effects and in the formulation of environmental policy by government agencies. This book features contributions from policy makers, scientists actively involved in collection of data, and professional, academic and government statisticians. These explore the interfaces between the different areas of...

Автор

Gregory Bock R.

Evolution of Hydrothermal Ecosystem...

Gregory Bock R.

Evolution of Hydrothermal Ecosystems on Earth (and Mars?)

This book explores the possibility that life exists on Mars. It provides an interdisciplinary overview of the early evolution of life in hydrothermal ecosystems on Earth, focusing on the problem of remote sensing and incorporating geological work relevant to the search for evidence of early life on Earth and Mars. It discusses the belief that studying thermal spring deposits as part of this search may be the best opportunity to test whether life on earth is a «unique experiment,» or whether...

Автор

Gregory Bock R.

Fatty Acid and Lipotoxicity in Obes...

Gregory Bock R.

Fatty Acid and Lipotoxicity in Obesity and Diabetes

The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book...

Автор

Gregory Bock R.

Generation and Effector Functions o...

Gregory Bock R.

Generation and Effector Functions of Regulatory Lymphocytes

Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much more detailed picture of these cells, they are still highly controversial. Several unresolved issues responsible for this dilemma are discussed in...

Автор

Gregory Bock R.

Genetics of Autoimmunity

Gregory Bock R.

Genetics of Autoimmunity

This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated. Incorporating data on disease-associated chromosomal loci that has been accumulated from inbred mice, the title: descibes how some susceptibility loci may be common to many diseases, whereas others are relatively disease specific discusses the importance of developing...

Автор

Gregory Bock R.

Genetics of Criminal and Antisocial...

Gregory Bock R.

Genetics of Criminal and Antisocial Behaviour

This book offers a fresh perspective on the controversial topic of criminal and antisocial behavior. It synthesizes findings from behavioral and population genetics, evolutionary biology and criminology and presents the latest findings in twin studies, adoption cohort studies, molecular genetics and animal models for human aggression. Also included is a detailed analysis of the legal implications of genetics and crime research and strategies for rehabilitation.

Автор

Gregory Bock R.

Growth Factors as Drugs for Neurolo...

Gregory Bock R.

Growth Factors as Drugs for Neurological and Sensory Disorders

Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.

Автор

Gregory Bock R.

Heart Failure

Gregory Bock R.

Heart Failure

Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling the cellular circuitry involved in cardiac failure, as well as in normal cardiac growth, development and apoptosis. This work has revealed new and unexpected therapeutic targets in the heart. In...

Автор

Gregory Bock R.

Higher-Order Processing in the Visu...

Gregory Bock R.

Higher-Order Processing in the Visual System

Foremost neurophysiologists and psychophysicists provide pertinent information on the nature of representation at the earliest stages as this will constrain the disposition of all subsequent processing. This processing is discussed in several different types of visual perception.

Автор

Gregory Bock R.

Immunoinformatics

Gregory Bock R.

Immunoinformatics

The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components....

Автор

Gregory Bock R.

Immunological Tolerance

Gregory Bock R.

Immunological Tolerance

This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, partial T cell activation, and the role of apoptosis in tolerance. Careful consideration is also given to the clinical applications of our understanding of immunological tolerance, with specific chapters dealing with T cell activation during tumour...

Автор

Gregory Bock R.

Molecular Approaches to Human Polyg...

Gregory Bock R.

Molecular Approaches to Human Polygenic Disease

Many common human diseases have a multifactorial origin: they are influenced by a person's genetic predisposition as well as by factors in the environment. This volume deals with the application of recombinant DNA techniques to the identification of diseases that have more than one inherited component. Focus is on the polygenic factors responsible for coronary atherosclerosis. Several other disorders having a polygenic origin are also discussed, including hypertension, diabetes mellitus,...

Автор

Gregory Bock R.

Molecular Mechanisms Influencing Ag...

Gregory Bock R.

Molecular Mechanisms Influencing Aggressive Behaviours

This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals. The extensive discussions deal with specific problems of interpretation at the molecular level, as well as general issues relating to our understanding of human and animal...

Автор

Gregory Bock R.

New Treatment Strategies for Dengue...

Gregory Bock R.

New Treatment Strategies for Dengue and Other Flaviviral Diseases

Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of dengue virus, of which DENV-2 has been the most prevalent in many recent epidemics. Following primary infection, lifelong immunity develops, preventing repeated assault by the same serotype. However, the non-neutralizing antibodies...

Автор

Gregory Bock R.

Non-Reproductive Actions of Sex Ste...

Gregory Bock R.

Non-Reproductive Actions of Sex Steroids

Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids' effects on the nervous and immune systems. Provides an integrated evaluation of the advantages and disadvantages of hormone replacement therapy.

Автор

Gregory Bock R.

Для правообладателей и по всем вопросам knigism.info@yandex.ru